Evaluation of the antimutagenic capacity of ethanolic extracts of Green Tea (Camellia sinensis)
DOI:
https://doi.org/10.47808/revistabioagro.v7i2.55Keywords:
antioxidant, antimutagen, phenols, phytochemicalsAbstract
At present, medicinal plants contain active ingredients, which although they are responsible for the therapeutic properties attributed to them, they are also responsible for the poisonings and adverse reactions that may occur if they are used in inappropriate doses or for prolonged periods. Therefore, the objective of the present work is to evaluate the possible antimutagenic capacity of the ethanolic extract of green tea (Camellia sinensis) based on its high antioxidant content reported. To this end, the antimutagenic activity was determined by means of the mutation and somatic recombination test (SMART), with a previous treatment of ethanolic extracts of green tea and subsequent treatment with a reference mutagen (O-Toluidine), evaluating the inhibition of spots or cell clones in the eye of Drosophila melanogaster. Regarding the results, it was observed that the ethanolic extract previously administered to the reference mutagen significantly inhibited genotoxic damage, being more effective for small than large spots. In general, the results suggested that the green tea extracts evaluated, have biological properties with a beneficial potential for human health and that can be used in preventive treatments against cancer or exposure related to mutagens in a work or natural way.
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Copyright (c) 2019 Alejandra Sarahi Hern´ández-Lozada, Juan Carlos Gaytán-Oyarzún, Maritza López-Herrera, Pablo Octavio Aguilar, Fabiola Guzmán Ortiz
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